The best available science makes clear that whole-plant cannabis preparations are quantifiably superior to single compounds because the plant’s complex mix of cannabinoids, terpenes, and flavonoidsinteract synergistically to create an “entourage effect” that enhances each other’s therapeutic effects.
Lots of people (like yours truly) enjoy the psychoactivity of cannabis and find it mood elevating and healing in and of itself, but rest assured that you don’t need to get high to reap the benefits of THC.
According to Project CBD:The successful use of cannabis as a medicine depends to a great extent on managing its psychoactive properties. The goal is to administer consistent, measurable doses of a CBD-rich cannabis remedy with as much THC as a person is comfortable with… Preclinical science lends credence to the notion that a small amount of THC can confer health benefits. Oral administration of a low dose of THC (1 mg/day) resulted in “significant inhibition of disease progression” in an animal model of atherosclerosis (hardening of the arteries), according to a 2005 report in Nature, which noted: “This effective dose is lower than the dose usually associated with psychotropic effects of THC.”CBD is essentially getting in the way of THC’s ability to bind the CB1 receptor, which is why the presence of CBD has a significant impact on the psychoactivity of THC-containing products, [and] why the ratio of the two compounds is important for anticipating the effectsof cannabis products… While THC and CBD have different pharmacological properties, they can both have similar physiological effects, probably acting through different mechanisms. For instance, both compounds can have analgesic and anti-inflammatory effects; they may act through different mechanisms, so having THC and CBD could potentially enhance an outcome surrounding pain relief.
If you’re fortunate enough to have access to a legally operating cannabis dispensary, you should have no problem finding flowers, concentrates, topicals, and edibles with a wide range of THC-to-CBD ratios. But patients and consumers still sourcing their cannabis from the underground market will encounter more difficulty. We plan to continue to grow a few low THC high CBD strains that many of our patients and myself have found to be extremely effective. We do not foresee having any product that does not contain some amount of THC and we plan to continue to have Cannabis medicines and not hemp products.
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